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Oral Health Prev Dent 18 (2020), Open Access 12. Feb. 2020
Oral Health Prev Dent 18 (2020), Open Access (12.02.2020)
Open Access CASE REPORT, Online Article, Page 1011-1016, doi:10.3290/j.ohpd.a45522, PubMed:33215492
Online Article: Mucormycosis in the Jaw: A Report of 2 Cases and Literature Review
Kwak, Eun-Jung / Kim, Dong-Jin / Nam, Woong / Park, Wonse
Mucormycosis is a rare fungal infection with high morbidity and mortality and a very poor prognosis. However, aggressive medical and surgical management can result in survival rates exceeding 80%. The most common sites involved in mucormycosis infection are the sinus, lung, skin and soft tissues, gastrointestinal system, central nervous system, and rarely the mandible. Systemic risk factors for mucormycosis are diabetes mellitus (DM), neutropenia, corticosteroid use, hematologic malignancies, organ transplantation, metabolic acidosis, deferoxamine use, and advanced age. Local risk factors are a history of trauma, burns, surgery. We report on two patients with mucormycosis of the jaw. While one case presented as mucormycois involving the maxillary sinus in a patient with uncontrolled DM, the other was a rare case of mandibular mucormycosis in a patient with acute myeloid leukemia.
Keywords: jaw, mucormycosis, necrosis, zygomycosis