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Oral Health and Preventive Dentistry
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Oral Health Prev Dent 18 (2020), No. 2     1. Apr. 2020
Oral Health Prev Dent 18 (2020), No. 2  (01.04.2020)

Open Access ORAL MEDICINE, Page 161-164, doi:10.3290/j.ohpd.a43359, PubMed:32099975


Does Streptococcus Salivarius Strain M18 Assumption Make Black Stains Disappear in Children?
Bardellini, Elena / Amadori, Francesca / Gobbi, Emanuela / Ferri, Anna / Conti, Giulio / Majorana, Alessandra
Purpose: This randomised controlled study evaluated the effectiveness of an oral probiotic, Streptococcus salivarius M18 (SsM18), in children with black stains (BSs) in order to counteract their reformation.
Materials and Methods: Fifty-eight children (aged 4–10 years) presenting with BSs were enrolled. They were randomly divided into two groups: group A (n = 29) included children who were given the test product containing SsM18 once a day for 3 months; group B (n = 29) included children who did not receive any treatment. Before beginning the study, all the children underwent professional removal of BSs. The assessment of BSs was done after 3 months (T1) and after 6 months (T2).
Results: Four patients (1 belonging to group A and 3 to group B) were excluded from the study because they started antibiotic therapy. After 3 months (T1), BSs were detected in 6 of the 28 children (21.2%) from group A and in 13 out of the 26 (50%) children from group B (p < 0.05). After 6 months (T2), BSs were detected in 9 out of the 28 (32.1%) children from group A and in 14 of the 26 (53.8%) children from group B (p > 0.05).
Conclusions: BSs formation in children could be prevented by administering S. salivarius M18.

Keywords: child, pigmentation, probiotics, teeth