We are using cookies to implement functions like login, shopping cart or language selection for this website. Furthermore we use Google Analytics to create anonymized statistical reports of the usage which creates Cookies too. You will find more information in our privacy policy.
OK, I agree I do not want Google Analytics-Cookies
Oral Health and Preventive Dentistry



Forgotten password?


Oral Health Prev Dent 14 (2016), No. 3     3. June 2016
Oral Health Prev Dent 14 (2016), No. 3  (03.06.2016)

Page 197-205, doi:10.3290/j.ohpd.a35745, PubMed:26973988

Minimally Invasive Treatment of White Spot Lesions - A Systematic Review
Abdullah, Zoha / John, Joseph
Purpose: To evaluate the efficacy of minimally invasive methods for the treatment of white-spot lesions involving fluorides, CPP-ACP (casein phosphopeptide-stabilised amorphous calcium phosphate) and resin infiltration vs a placebo or control.
Materials and Methods: According to predetermined criteria, four databases were searched for eligible studies. References of the selected articles and relevant reviews were searched for any missed publications.
Results: Eight randomised controlled trials were selected as eligible studies, and only qualitative analyses were performed because of the diversity of the interventions and outcome measures. Three studies showed significant effects of three different fluoride preparations and used DIAGNOdent and ICDAS to assess the white spot lesions. Both studies comparing resin infiltration to a placebo showed significant effects in treating white spot lesions. One study using CPP-ACP showed a significant improvement in the lesions post treatment.
Conclusion: Evidence suggests minimally invasive treatment modalities of white spot lesions produced significant improvement in the appearance and regression of white spot lesions following treatment when compared to a control or placebo.

Keywords: CPP-ACP, dental caries, fluorides, resin infiltration, white spot lesions