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Oral Health & Preventive Dentistry



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Oral Health Prev Dent 11 (2013), No. 2     10. June 2013
Oral Health Prev Dent 11 (2013), No. 2  (10.06.2013)

Page 191-196, doi:10.3290/j.ohpd.a29736, PubMed:23757456

Remineralisation of Occlusal White Spot Lesion with a Combination of 10% CPP-ACP and 0.2% Sodium Fluoride Evaluated Using Diagnodent: A Pilot Study
Fredrick, Chain / Krithikadatta, Jogikalmat / Abarajithan, Mohan / Kandaswamy, Deivanayagam
Purpose: To evaluate the efficacy of 10% casein phosphopeptide amorphous calcium phosphate complex (CPP-AC P) used alone or with fluoride as compared to fluoride mouthrinse for the remineralisation of occlusal white spot lesions in an in vivo pilot study.
Materials and Methods: Forty-five subjects with occlusal white spot lesions (WSL) determined by visual examination and confirmed with Diagnodent were randomly divided into 3 groups: group 1: 10% CPP-AC P + 0.2% NaF; group 2: 10% CPPAC P; group 3: 0.5% NaF mouthrinse for 30 days. The pre-treatment and post-intervention Diagnodent values were tabulated and subjected to statistical analysis.
Results: Among the groups, the remineralising potential of 10% CPP-AC P + 0.2% NaF (group 1) and 10% CPP-AC P (group 2) were similar, however, both groups were superior to 0.5% NaF mouthrinse (group 3).
Conclusions: The CCP-AC P technique is highly beneficial for the remineralisation of non-cavitated occlusal white spot lesions when compared to 0.5% NaF mouthrinse.

Keywords: casein phosphopeptide amorphous calcium phosphate complex (CPP-AC P), diagnodent, fluoride, remineralisation, white spot lesion